Recombinant growth factor mixtures induce cell cycle progression and the upregulation of type I collagen in human skin fibroblasts, resulting in the acceleration of wound healing processes.

Recombinant growth factor mixtures induce cell cycle progression and the upregulation of type I collagen in human skin fibroblasts, resulting in the acceleration of wound healing processes.

Model: Acute skin wound model in mice, with parallel in vitro human skin fibroblast experiments

Growth factor mixture treated mice showed accelerated wound closure from day 7, greater re-epithelialisation and reduced inflammatory cell infiltration compared with phosphate-buffered saline treated mice.

Extraction: extract · Supplied extraction confidence: 0.5. Machine-extracted fields require source verification.