Effects of tenoxicam in experimental corrosive esophagitis model.
RatBurnChemical / corrosiveWistar albinon = 24 rats in total, 8 per group (tenoxicam, control, sham)0.5 mg/kg/dayStarted after experimental induction of the oesophageal burn
Model: Experimentally induced corrosive (caustic) oesophageal burn
Histopathological damage score was significantly higher in the control group (p < 0.005). Intense inflammation was seen in six of eight control rats with fibroblast proliferation graded 5+/3-, versus inflammation 3+/5- and fibroblast proliferation 3+/5- in the tenoxicam group. No inflammation or fi…
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