Vagal nerve stimulation modulates the dendritic cell profile in posthemorrhagic shock mesenteric lymph.
RatHaemorrhage/shockControlledSprague-DawleyMaleDirect electrical stimulation of the cervical vagus nerveAfter the haemorrhagic shock phase
Model: Trauma and haemorrhagic shock: midline laparotomy with 60 minutes of haemorrhagic shock to a blood pressure of 35 mmHg followed by fluid resuscitation
Vagal nerve stimulation reduced histological gut injury and mesenteric lymph flow, prevented the injury-induced fall in CD103+ MHC-II+ dendritic cells in mesenteric lymph and restored regulatory T cell numbers in the mesenteric lymph node.
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