Oral erlotinib, but not rapamycin, causes modest acceleration of bladder and hindlimb recovery from spinal cord injury in rats.
RatSpinal cord injuryContusionSprague-DawleyFemaleOral (erlotinib)Started directly after contusion injury, during the acute phase
Model: Spinal cord contusion injury
Erlotinib accelerated locomotor recovery and slightly improved bladder recovery but produced no long-term locomotor improvement. Rapamycin improved neither locomotor nor bladder recovery. Neither regimen improved long-term functional outcome.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.