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PRECLINICAL PUBLICATION · 2014

The anti-inflammatory effects of Caragana tangutica ethyl acetate extract.

Mixed / Endotoxin/LPS

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 24406787 ↗2014Reported benefit

The anti-inflammatory effects of Caragana tangutica ethyl acetate extract.

MixedEndotoxin/LPSSprague-Dawley (rats)Male100, 200 and 400 mg/kg

Model: Lipopolysaccharide-induced acute lung injury in mice, with xylene-induced ear oedema, carrageenan-induced paw oedema and acetic acid-induced writhing models

The extract significantly reduced xylene-induced ear oedema at 100, 200 and 400 mg/kg, reduced carrageenan-induced paw oedema at 3 hours, reduced acetic acid writhing dose-dependently, and reduced lipopolysaccharide-induced acute lung injury through inhibition of prostaglandin E2 release and COX-2…

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.