Antimicrobial efficacy and wound-healing property of a topical ointment containing nitric-oxide-loaded zeolites.
MixedWoundZucker obese ratsmaleTopicalMinimum microbicidal concentrations in vitro 50 to 100 mg o…
Model: Full-thickness cutaneous wounds in Zucker obese rats, with parallel in vitro infection models using Escherichia coli, Acinetobacter baumannii, Staphylococcus epidermidis, meticillin-resistant Staphylococcus aureus and Candida albicans
Five to eight log reductions in bacterial viability and three log reductions in fungal viability were seen after 8 hours of exposure compared with untreated organisms, while 3T3 fibroblasts remained viable after 24 hours at the same concentration. Full-thickness cutaneous wounds on Zucker obese rat…
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.