Intravenous multipotent adult progenitor cell therapy attenuates activated microglial/macrophage response and improves spatial learning after traumatic brain injury.
RatTBIControlled cortical impactmaleIntravenousTwo concentrations: 2 million cells per kilogram and 10 mil…2 hours and 24 hours after cortical contusion injury
Model: Controlled cortical impact traumatic brain injury
At 120 days after injury the high dose group (10 million cells per kilogram) showed significant improvement in left hind limb deficit on the balance beam, decreased latency to platform and distance travelled on day 5 of Morris water maze testing, and decreased proximity measure on probe trials indi…
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