Morphological validation of hydroxyethylstarch use during the acute period of severe brain injury
RatTBIUnspecifiedWistarMaleIntravenousAcute period after severe brain injury
Model: Severe brain injury in rats studied during the acute post-injury period with assessment of the cerebral microcirculatory bed and blood-brain barrier
Intravenous 10 percent hydroxyethyl starch produced positive changes in the morphometric values of cerebral capillaries, with reduced vascular permeability and reduced cerebral tissue oedema, supporting its use as a component of infusion therapy in severe brain injury.
Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.