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← Studies/PMID 23934512
PRECLINICAL PUBLICATION · 2013

Chemokine CCL2 induces apoptosis in cortex following traumatic brain injury.

Rat / TBI

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Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 23934512 ↗2013Reported benefit

Chemokine CCL2 induces apoptosis in cortex following traumatic brain injury.

RatTBIWeight-drop / impact-accelerationSprague-DawleyMaleAssessed 3 days after injury

Model: Local cortical traumatic brain injury induced by Feeney weight-drop

CCL2 and CCR2 mRNA rose for at least 10 days after injury, peaking at day 3, and the CCR2 antagonist RS504393 reduced TUNEL staining and improved Morris water maze performance at 3 days.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.