Effects of a novel herbal formulation JSK on acute spinal cord injury in rats.
RatSpinal cord injuryContusionWistarFemalen = 12 for behavioural assessment, 6 for histology and immunoch…Oral gavageFirst dose 24 h after injury
Model: Acute contusion spinal cord injury produced with a New York University impactor
JSK improved locomotor function (n = 12, p < 0.05), reduced tissue damage (p < 0.01, n = 6) and preserved axons and myelin, with increased neuroglobin, vascular endothelial growth factor and growth-associated protein 43 and reduced caspase 3, cyclooxygenase-2, RhoA and fibrinogen
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.