Therapeutic option for managing lung injury induced by infrarenal aortic cross-clamping.
RatIschaemia-reperfusionRenalWistarMale
Model: Infrarenal aortic exclusion for 180 min followed by 4 h reperfusion, with remote lung injury
Postconditioning reduced lung histological damage, free radicals, TNF-alpha, myeloperoxidase activity, HSP72 and wet/dry ratio, and improved arterial pO2 during early reperfusion.
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