Exogenous normal lymph alleviates lipopolysaccharide-induced acute kidney injury in rats.
RatEndotoxin/LPSWistarIntravenous5 mL/kg infused at 0.5 mL per minute15 min after lipopolysaccharide injection
Model: Acute kidney injury induced by jugular vein injection of lipopolysaccharide 15 mg/kg
Exogenous normal lymph reduced plasma urea and creatinine, lowered renal ICAM-1 and myeloperoxidase, and preserved Na+/K+-ATPase activity after lipopolysaccharide challenge.
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