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PRECLINICAL PUBLICATION · 2013

Neuroprotective effect of suppression of astrocytic activation by arundic acid on brain injuries in rats with acute subdural hematomas.

Rat / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 23685194 ↗2013Reported benefit

Neuroprotective effect of suppression of astrocytic activation by arundic acid on brain injuries in rats with acute subdural hematomas.

RatTBIUnspecifiedWistarMale

Model: Acute subdural haematoma model with secondary ischaemic injury beneath the haematoma

Arundic acid reduced S100 protein expression, infarction volume and apoptotic cell numbers around ischaemic lesions without changing aquaporin 4 expression.

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.