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PRECLINICAL PUBLICATION · 2013

The effect of RHIZOMA COPTIDIS and COPTIS CHINENSIS aqueous extract on radiation-induced skin injury in a rat model.

Rat / Radiation

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 23675786 ↗2013Reported benefit

The effect of RHIZOMA COPTIDIS and COPTIS CHINENSIS aqueous extract on radiation-induced skin injury in a rat model.

RatRadiationMale and femalen = 5 rats per group euthanised at each of 2 and 49 days after…

Model: Radiation-induced skin injury from a single 45 Gy dose of beta-ray irradiation

RCE reduced radiation-induced skin damage on histology, lowered serum and skin malondialdehyde (4.57 plus or minus 0.21 versus 5.54 plus or minus 0.21 mmol/ml in serum at 2 days) and limited the fall in superoxide dismutase activity.

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.