Neuroprotective effect of acute interferon-beta 1B treatment after spinal cord injury.
RatSpinal cord injuryContusionSprague-DawleyMalen = 24 rats in 3 groupsAfter injury (acute treatment); exact interval not stated
Model: Weight-drop contusion spinal cord injury
Interferon beta-1b increased tissue heat shock protein 70 and reduced leucocyte infiltration, haemorrhage, oedema and necrosis compared with saline and control groups.
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