Photobiomodulation by helium neon and diode lasers in an excisional wound model: A single blinded trial.
RatWoundAlbino WistarMalen = 24 animals in 4 groups, stated as 6 per group; the same Met…Topical irradiation over the wound via fibre optic delivery systemEnergy densities 18 J/cm2 (diode, group L1), 8 J/cm2 (heliu…Animals stabilised for at least 2 days after wounding before the treatment cour…
Model: Full-thickness circular excisional skin wound on the shaved dorsum, created with a stencil, scalpel and scissors, left open to heal
No laser group raised tissue hydroxyproline significantly above control, but helium-neon at 8 J/cm2 produced clear re-epithelialisation and reduced inflammation, whereas 3.38 J/cm2 delayed re-epithelialisation.
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