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PRECLINICAL PUBLICATION · 2013

Licofelone modulates neuroinflammation and attenuates mechanical hypersensitivity in the chronic phase of spinal cord injury.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 23303944 ↗2013Mixed findings

Licofelone modulates neuroinflammation and attenuates mechanical hypersensitivity in the chronic phase of spinal cord injury.

RatSpinal cord injuryContusionChronic phase of injury, approximately 9 months after contusion

Model: Moderate thoracic spinal contusion injury, assessed 9 months after injury

Licofelone raised endogenous anti-oxidant and anti-inflammatory metabolites at the chronic lesion site and reduced mechanical, but not thermal, hindpaw hypersensitivity.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.