Improvement of lipopolysaccharide-induced hepatic injuries and inflammation with mulberry extracts.
RatEndotoxin/LPSSprague-DawleyMale0.5 and 1 g/kg1 h before lipopolysaccharide injection
Model: Acute liver injury induced by lipopolysaccharide injection at 5 mg/kg
Pre-treatment with mulberry water extract prevented lipopolysaccharide-induced rises in liver enzymes and lipids, suppressed hepatic malondialdehyde formation and reduced hepatic COX-2, NF-kappa B and iNOS expression.
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.