In vivo wound healing activity and phytochemical screening of the crude extract and various fractions of Kalanchoe petitiana A. Rich (Crassulaceae) leaves in mice.
MixedWoundTopical ointment or gel; oral administration for the dead-space model5% and 10% topical formulations; 300 and 600 mg/kg orally i…
Model: Excision, incision and dead-space wound models in mice, with skin irritation testing in rats and rabbit
Ointment of the crude extract at 5% and 10% significantly improved healing in excision and incision models (p < 0.01), the aqueous and methanolic fractions increased wound contraction, shortened epithelialisation time, raised hydroxyproline content (p < 0.05) and increased skin breaking strength (p…
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.