Effects of acute sacral neuromodulation on bladder reflex in complete spinal cord injury rats.
RatSpinal cord injuryComplete transectionSprague-Dawleyfemalen = 12 adult female rats in total, 4 per group (intact, spinal…Sacral nerve electrical stimulation under anaesthesiaAcute stimulation applied after spinal transection during cystometry
Model: Complete spinal cord transection at T9 to T10 producing neurogenic overactive bladder
Acute sacral neuromodulation lengthened bladder contraction period and duration and lowered bladder peak pressure in spinal cord injured rats, indicating inhibition of bladder overactivity.
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