PRECLINICAL PUBLICATION · 2013

Hydrogen sulfide prevents hyperoxia-induced lung injury by downregulating reactive oxygen species formation and angiopoietin-2 release.

Mouse / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 23092319 ↗2013Reported benefit

MouseOtherC57BL/610 mg/kgGiven with hyperoxia exposure

Model: Hyperoxia induced acute lung injury, 90 vol% oxygen exposure

Sodium hydrosulfide abolished the morphological features of hyperoxic lung injury and significantly reduced angiopoietin-2 expression in vivo.

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.