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PRECLINICAL PUBLICATION · 2012

Rat model of burn wound healing: effect of Botox.

Rat / Burn

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 23034258 ↗2012Mixed findings

Rat model of burn wound healing: effect of Botox.

RatBurnUnspecifiedSprague-Dawleyn = 50 rats divided into two groupsIntralesional injection

Model: Second-degree burn of 5 cm2

Botulinum toxin type A produced relatively faster regeneration, delayed lower grade inflammation and increased fibroblast numbers on histology with improved scar appearance, but transepidermal water loss did not differ significantly from saline apart from slightly better moisture preservation.

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.