PRECLINICAL PUBLICATION · 2012

Electrospun chitosan/polyvinyl alcohol nanofibre mats for wound healing.

Rat / Wound

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

Electrospun chitosan/polyvinyl alcohol nanofibre mats, prepared with chitosan aqueous salts formed using hydroxybenzotriazole, thiamine pyrophosphate or EDTA

PMID 22925275 ↗2012Reported benefit

Electrospun chitosan/polyvinyl alcohol nanofibre mats for wound healing.

RatWoundWistarMaleTopical application as a wound dressing

Model: Acute excisional skin wound used for in vivo wound healing testing of dressings

Chitosan-EDTA/polyvinyl alcohol nanofibre mats decreased acute wound size more than gauze during the first week after wounding. The mats were non-toxic to normal human fibroblasts and the chitosan-hydroxybenzotriazole and chitosan-EDTA formulations showed antibacterial activity.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.