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PRECLINICAL PUBLICATION · 2012

Low-power laser therapy for repairing acute and chronic-phase bone lesions.

Rat / Fracture

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 22850224 ↗2012Reported benefit

Low-power laser therapy for repairing acute and chronic-phase bone lesions.

RatFractureUnspecifiedWistarMalen = 63 adult male rats in nine groups; subgroups of n = 7 analy…Transcutaneous irradiation over the bone lesion90 J/cm2Treatment started in either the acute phase or the chronic phase of the bone in…

Model: Surgically created bone lesion (osteotomy), assessed on days 9, 17 and 28 after surgery

Animals treated in the acute phase showed a more extensive endochondral ossification process. Laser-treated animals had significantly increased serum alkaline phosphatase and a gradual increase in bone stiffness. Effects were more prominent when treatment began during the acute phase.

Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.