Long-term administration of amnion-derived cellular cytokine suspension promotes functional recovery in a model of penetrating ballistic-like brain injury.
RatTBIPenetrating / ballisticSprague-DawleyMaleContinuous intracerebral infusionOptimal infusion rate 1 microlitre per hourInitiated 15 minutes after injury in the main experiment; a separate experiment…
Model: Penetrating ballistic-like brain injury
ACCS was thermally stable for 1 week at 37 degrees C and protected neurites against staurosporine toxicity in vitro. Long-term infusion at 1 microlitre per hour significantly reduced injury-induced neuropathology and motor abnormalities but was not sufficient to reduce cognitive deficits. Neuroprot…
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