Vagal nerve stimulation decreases blood-brain barrier disruption after traumatic brain injury.
MouseTBIWeight-drop / impact-accelerationBALB/cMaleDirect vagal nerve stimulation10 minutes of stimulationImmediately before injury
Model: Weight-drop severe traumatic brain injury
At 6 h, TBI increased cerebral vascular permeability approximately fourfold versus sham. VNS reduced permeability compared with TBI alone and returned perivascular aquaporin 4 expression to near sham levels.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.