PRECLINICAL PUBLICATION · 2012

The n-Hexane, ethylacetate, and butanol fractions from Hydnocarpi Semen enhanced wound healing in a mice ulcer model.

Mouse / Wound

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

Hydnocarpi Semen n-hexane, ethyl acetate and butanol fractions

PMID 22537169 ↗2012Reported benefit

The n-Hexane, ethylacetate, and butanol fractions from Hydnocarpi Semen enhanced wound healing in a mice ulcer model.

MouseWoundICRMaleButanol fraction effective at 2 mg/kg

Model: Diabetic skin ulcer wound model

All three fractions promoted wound healing, with the butanol fraction the most potent; wound area score decreased significantly even at 2 mg/kg. MMP-9 expression and activity were highest in the butanol fraction group.

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.