Investigation of the mechanisms underlying the gastroprotective effect of cymbopogon citratus essential oil.
MouseChemical/toxinOral pretreatmentPretreatment before the necrotizing agent
Model: Gastric ulceration induced by absolute ethanol and by aspirin
EOCC showed a dose-independent anti-ulcer effect, with a preventive index of 88% in the ethanol model and 76% in the aspirin model. Indomethacin partially suppressed gastroprotection (48.5%), whereas L-NAME (85.2%), glibenclamide (100%) and yohimbine (79.7%) did not attenuate it.
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.