Acute neuroprotective effects of extremely low-frequency electromagnetic fields after traumatic brain injury in rats.
RatTBIFluid percussionSprague-DawleyMaleWhole-body electromagnetic field exposure15 Hz fields at intensities of 1 G, 3 G and 5 GExposure after lateral fluid percussion injury, with kainic acid challenge from…
Model: Lateral fluid percussion injury
Exposure to 15 Hz extremely low-frequency electromagnetic fields lowered hypoxia-inducible factor-1alpha expression, reduced kainic acid-induced hippocampal apoptosis and shortened water maze escape time. Blood-brain barrier recovery was accelerated and the window of neuroprotection was prolonged.
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