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PRECLINICAL PUBLICATION · 2012

Atropa belladonna L. water extract: modulator of extracellular matrix formation in vitro and in vivo.

Rat / Wound

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 22480427 ↗2012Reported benefit

Atropa belladonna L. water extract: modulator of extracellular matrix formation in vitro and in vivo.

RatWoundSprague-DawleyMaleTopical application to the woundTwo different concentrations of the extract (values not sta…Applied daily after wounding

Model: Single round full-thickness skin wound on the back

Atropa belladonna water extract induced fibronectin and galectin-1 rich extracellular matrix formation both in vitro and in vivo. Keratinocyte proliferation was also increased, indicating the extract modulates skin wound healing.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.