New bioactive motifs and their use in functionalized self-assembling peptides for NSC differentiation and neural tissue engineering.
MixedSpinal cord injuryContusionImplantation of the hydrogel scaffold at the injury site
Model: Acute contusive spinal cord injury
The functionalised self-assembling peptide Ac-FAQ supported the highest neural stem cell viability and differentiation in vitro and, when implanted after contusive spinal cord injury, promoted nervous tissue regrowth and improved locomotor recovery. Non-functionalised LDLK12 gave intermediate axon…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.