Topical treatment of oral cavity and wounded skin with a new disinfection system utilizing photolysis of hydrogen peroxide in rats.
RatWoundWistarMaleTopical application1 M hydrogen peroxide with laser irradiationApplied immediately after wounding for the skin experiment
Model: Full-thickness skin wounds and intact buccal oral mucosa
The photolytic hydrogen peroxide system substantially reduced Staphylococcus aureus colony forming units within 2 min. No abnormal histological findings were seen in treated buccal mucosa or in healing full-thickness skin wounds, indicating low acute local injurious potential rather than a healing…
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