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PRECLINICAL PUBLICATION · 2012

Protective effect of triphala on radiation induced acute intestinal mucosal damage in Sprague Dawley rats.

Rat / Radiation

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 22439434 ↗2012Reported benefit

Protective effect of triphala on radiation induced acute intestinal mucosal damage in Sprague Dawley rats.

RatRadiationSprague-DawleyMalen = 30 rats in total, 6 per group across 5 groupsOral1 g/kg/day or 1.5 g/kg/dayGiven before irradiation, for 5 consecutive days before irradiation or for 10 c…

Model: Single fraction of 12.5 Gy gamma irradiation (iridium-192) on day 5 inducing rectal mucosal damage

High-dose triphala at 1.5 g/kg/day for 10 days significantly improved surface epithelium, glandular and lamina propria scores compared with irradiation alone. The glandular recovery was significantly better than with the lower dose or the shorter 5-day schedule.

Extraction: extract · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.