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PRECLINICAL PUBLICATION · 2012

Metallothionein-II improves motor function recovery and increases spared tissue after spinal cord injury in rats.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 22405890 ↗2012Reported benefit

Metallothionein-II improves motor function recovery and increases spared tissue after spinal cord injury in rats.

RatSpinal cord injuryContusionWistarFemale3.2, 10 and 100 microgram2 h and 8 h after spinal cord injury

Model: Thoracic spinal cord contusion using a computer-controlled NYU impactor

MT-II at 10 and 100 microgram raised 8-week BBB scores (12.63 and 10.88 versus 7.88 in controls) and increased spared tissue; 3.2 microgram had no effect.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.