PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2012

Human platelet-rich plasma- and extracellular matrix-derived peptides promote impaired cutaneous wound healing in vivo.

Mouse / Wound

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 22384158 ↗2012Reported benefit

Human platelet-rich plasma- and extracellular matrix-derived peptides promote impaired cutaneous wound healing in vivo.

MouseWoundBALB/cn = 9 to 15 animals per treatment group (3-5 animals per group…Topical to the wound, injected under the dressings using a 25G needle1 mg/mL comb1 and 284 microgram/mL UN3, suspended in 3% car…From 24 h after injury

Model: Cranial dermal wounds in mice treated with cyclophosphamide to impair wound healing

comb1 and UN3, alone and combined, improved epithelialisation, granulation tissue and collagen deposition and roughly doubled wound vessel density in impaired wounds.

Extraction: extract · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.