Possible molecular mechanism of promotion of repair of acute Achilles tendon rupture by low intensity-pulsed ultrasound treatment in a rat model.
RatOtherSprague-DawleyMalen = 98 male Sprague-Dawley ratsTranscutaneous application over the injured tendonFrequency 1.5 MHz, repetition cycle 1.0 kHz, burst width 20…
Model: Surgical rupture of the Achilles tendon at the attachment site and musculotendinous junction under direct vision
LIPUS accelerated Achilles tendon repair relative to the untreated group on electron microscopy. COX-2 and EP4 were over-expressed in the LIPUS group during the inflammatory period, and TGF-beta1 was markedly induced followed by collagen expression during repair and reconstitution.
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