MC3T3-E1 osteoprogenitor cells systemically migrate to a bone defect and enhance bone healing.
MouseFractureFemurNude miceIntracardiac injection into the left ventricle to avoid pulmonary sequestrationAfter creation of the femoral defect
Model: Drilled bone defect in the left femoral shaft
MC3T3-E1 cells systemically migrated to the femoral bone defect and bone mineral density at the defect was significantly increased compared with saline-injected controls.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.