PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2012

Inhaled hydrogen sulfide induces suspended animation, but does not alter the inflammatory response after blunt chest trauma.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 22089191 ↗2012Mixed findings

Inhaled hydrogen sulfide induces suspended animation, but does not alter the inflammatory response after blunt chest trauma.

RatOtherSprague-DawleyMaleInhalation100 ppm continuous flowStarted immediately after trauma

Model: Blunt chest trauma (blast wave) pulmonary contusion

Hydrogen sulfide lowered body temperature and activity and partially attenuated mediator release in lavage and in Kupffer and splenic cell supernatants, and abrogated the rise in alveolar macrophages at 48 h, but did not alter neutrophil counts or mononuclear cell responses, and showed no overall p…

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