Calcium-based nanoparticles accelerate skin wound healing.
MouseWoundBALB/cFemaleIntravenous (tail vein) and, in separate experiments, topical application to the wound bed100 microlitres of calcium-based nanoparticle solution per…Immediately following cutaneous injury
Model: Bilateral dorsal cutaneous excisional wounds
Intravenously administered calcium-based nanoparticles localised to the wound, acutely accelerated wound closure largely through contracture, and increased fibroblast calcium uptake, collagen lattice contraction and proliferation, whereas intravenous calcium chloride caused tetany and roughly 20 pe…
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