Effect of the lectin of Bauhinia variegata and its recombinant isoform on surgically induced skin wounds in a murine model.
MouseWoundSwiss albinoMalen = 84 mice, seven groups of 12Topical200 micrograms per mL solution, single daily dose of 20 mic…Started immediately after the surgical procedure
Model: Surgically created dorsal excisional skin wound
Wound closure was fastest with rBVL-1, complete by postoperative day 7, while the native lectin closed wounds by day 12 and outperformed controls, with reconstruction of all skin layers and increased keratin deposition.
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