Combination of activated Schwann cells with bone mesenchymal stem cells: the best cell strategy for repair after spinal cord injury in rats.
RatSpinal cord injuryContusionWistarFemaleTransplantation into the injured epicentre of the spinal cordAcutely after injury
Model: Acute contusive spinal cord injury using the New York University impactor, 10 g weight dropped 50 mm
Co-transplantation produced more regenerating corticospinal axons crossing the lesion, the smallest astrocytic population at the epicentre, more complete myelin sheaths and better hindlimb functional recovery than either cell type alone or medium.
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