PRECLINICAL PUBLICATION · 2011

Effect of flavonoids from Prosthechea michuacana on carbon tetrachloride induced acute hepatotoxicity in mice.

Mouse / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

Flavonoids isolated from Prosthechea michuacana bulbs (scutellarein 6-methyl ether, dihydroquercetin, apigenin 7-O-glucoside, apigenin-7-neohesperidoside and a new flavonol glycoside)

PMID 22014261 ↗2011Reported benefit

Effect of flavonoids from Prosthechea michuacana on carbon tetrachloride induced acute hepatotoxicity in mice.

MouseChemical/toxinMale

Model: Carbon tetrachloride-induced acute hepatotoxicity

Flavonoid treatment prevented the biochemical changes induced by carbon tetrachloride, with compounds 1, 4 and 5 showing hepatoprotection comparable with silymarin.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.