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PRECLINICAL PUBLICATION · 2011

Protective effect of vanillin against carbon tetrachloride (CCl4)-induced oxidative brain injury in rats.

Rat / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21986887 ↗2011Reported benefit

Protective effect of vanillin against carbon tetrachloride (CCl4)-induced oxidative brain injury in rats.

RatChemical/toxinWistarMalen = 32 rats divided into four groupsIntraperitoneal150 mg/kg/day intraperitoneally; carbon tetrachloride given…

Model: Acute oxidative brain injury induced by a single intraperitoneal injection of carbon tetrachloride (1 mL/kg)

Vanillin significantly protected the brain, decreasing lipid peroxidation and nitrite levels and elevating antioxidative enzyme activities and glutathione, blocking carbon tetrachloride induced oxidative brain damage.

Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.