Fermented barley extract supplementation maintained antioxidative defense suppressing lipopolysaccharide-induced inflammatory liver injury in rats.
RatEndotoxin/LPSWistarMaleOral (dietary supplementation)Supplemented for 10 days before the lipopolysaccharide challenge
Model: Lipopolysaccharide challenge producing acute inflammatory liver injury and oxidative stress
After lipopolysaccharide challenge, supplemented rats showed decreases in plasma interleukin-1 beta, interleukin-6 and tumour necrosis factor alpha of 25, 34 and 35 per cent respectively, a 44 per cent fall in plasma alanine aminotransferase, sustained hepatic antioxidative enzymes, and reductions…
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