Post-injury delivery of rAAV2-CNTF combined with short-term pharmacotherapy is neuroprotective and promotes extensive axonal regeneration after optic nerve trauma.
RatOtherWistarFemaleIntravitrealAt time of injury plus 3 and 10 days postoperatively
Model: Optic nerve transection with peripheral nerve graft
rAAV2-CNTF gene delivery combined with short-term CNTF and cAMP support increased retinal ganglion cell survival and axonal regeneration after optic nerve trauma.
Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.