Pentadecapeptide BPC 157 reduces bleeding time and thrombocytopenia after amputation in rats treated with heparin, warfarin or aspirin.
RatWoundWistarMaleIntravenous, intraperitoneal or intragastric10 ug/kg or 10 ng/kgImmediately after challenge
Model: Tail/limb amputation with heparin, warfarin or aspirin
BPC 157 reduced bleeding time and thrombocytopenia and prolonged survival after amputation in anticoagulant-treated rats.
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