Delayed anti-nogo-a antibody application after spinal cord injury shows progressive loss of responsiveness.
RatSpinal cord injuryUnspecifiedLewisFemaleIntrathecal infusionAcute, or 1 or 2 weeks delayed
Model: Large incomplete thoracic spinal cord injury
Anti-Nogo-A antibody promoted corticospinal regeneration and functional recovery when given acutely or at 1 week but not at 2 weeks after injury.
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