PRECLINICAL PUBLICATION · 2011

Activation of spinal and supraspinal cannabinoid-1 receptors leads to antinociception in a rat model of neuropathic spinal cord injury pain.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21813113 ↗2011Mixed findings

RatSpinal cord injuryCompressionSprague-DawleyMaleIntrathecal or intracerebroventricular4 weeks after injury

Model: Acute mid-thoracic spinal cord compression with neuropathic pain

CB1 agonist WIN 55,212-2 produced antinociception in neuropathic spinal cord injury pain whereas the CB1 blocker hemopressin did not.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.