PRECLINICAL PUBLICATION · 2011

Mu opioid signaling protects against acute murine intestinal injury in a manner involving Stat3 signaling.

Mouse / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21801866 ↗2011Reported benefit

MouseChemical/toxinC57BLSubcutaneousDaily during DSS exposure and recovery

Model: Dextran sodium sulfate (DSS)-induced intestinal injury

Mu opioid receptor activation attenuated DSS-induced intestinal injury and promoted healing via Stat3 signalling.

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.