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PRECLINICAL PUBLICATION · 2011

2',4',6'-Tris(methoxymethoxy) chalcone (TMMC) attenuates the severity of cerulein-induced acute pancreatitis and associated lung injury.

Mouse / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21778460 ↗2011Reported benefit

2',4',6'-Tris(methoxymethoxy) chalcone (TMMC) attenuates the severity of cerulein-induced acute pancreatitis and associated lung injury.

MouseChemical/toxinC57BLPretreatment and posttreatment

Model: Cerulein hyperstimulation acute pancreatitis with lung injury

TMMC reduced the severity of cerulein-induced acute pancreatitis and associated lung injury by inhibiting NF-kB/ERK signalling.

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.